Geminin Is Required for Zygotic Gene Expression at the Xenopus Mid-Blastula Transition
Figure 7
Treatments that Suppress Zygotic Gene Expression Cause DNA Damage.
Two-cell Xenopus embryos were injected on both sides with anti-Geminin MOs and/or RNA encoding the indicated proteins. The levels of S345-phosphorylated Chk1, S139-phosphoryated H2A.X, and Geminin were determined by immunoblotting.