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DR6 as a Diagnostic and Predictive Biomarker in Adult Sarcoma

Figure 3

Sarcoma patients have significant elevation of DR6 serum protein.

A. DR6 protein expression in a panel of 39 healthy controls and 71 patients with adult sarcoma. B DR6 levels in healthy controls and in sarcoma patients separated into chemo-naïve and chemo-refractory sub-groups. C. Receiver operator characteristic (ROC) curve for DR6 serum level in sarcoma patients versus controls. Area under the curve is 82.1%. D. Sarcoma patient DR6 serum protein levels based on histologic subtype. Averages are indicated by a long horizontal line. Brackets indicate standard deviations.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0036525.g003