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Development of Protective Autoimmunity by Immunization with a Neural-Derived Peptide Is Ineffective in Severe Spinal Cord Injury

Figure 1

Motor recovery of spinal cord injured rats.

Animals were subjected to a moderate (A) or severe spinal cord contusion (B). The recovery of rats subjected to a complete SCT is also shown (C). In all cases, animals were treated either with A91 or PBS. Severe injuries abolished the beneficial effect induced by immunizing with A91. * Different from PBS group (p<0.05, two-way ANOVA for repeated measures). Each point represents the mean ± SD of 10 rats.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0032027.g001