Contrasting Roles for CD4 vs. CD8 T-Cells in a Murine Model of Virally Induced “T1 Black Hole” Formation
Figure 4
We measured TMEV viral load on day 7 following TMEV infection of RAG-1 deficient mice that underwent adoptive transfer of CD4 or CD8 T-cells, respectively. Overall, the viral loads aren't different (p = 0.62) between the two groups, demonstrating that the observed T1BH formation isn't directly related to viral load.