Role for a Novel Usher Protein Complex in Hair Cell Synaptic Maturation
Figure 5
Usher proteins are present at the apical and basal aspects of P3 hair cells.
Isolated hair cells were immunostained for the Usher proteins (green) and myosin7A (magenta) and counter-stained with phalloidin (red). Arrowheads: Usher staining at the base of the hair cells. Asterisks: apical staining and co-localization with phalloidin. A a′, a″: CDH23. B, b′, b″: VLGR1, C, c′, c″: PCDH15, D, d′, d″: clarin-1. Scale bar: A–D: 2 µm; a′–d″: 4 µm.