Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30
Figure 3
Crystal structures of TDRD3 with methyl-arginine mimics.
(A) TDRD3 in complex with tetraethylene glycol (PG4). (B) TDRD3 in complex with isopropanol. The aromatic cage residues and small molecules are displayed in a stick model. (C) Superposition of the crystal structures of TDRD3 and SMN (PDB: 1MHN). The tetraethylene glycol molecule is shown in a stick model. SMN is colored in blue and TDRD3 is colored in green.