Faster HIV-1 Disease Progression among Brazilian Individuals Recently Infected with CXCR4-Utilizing Strains
Figure 3
Associations between inferred tropism and time to CD4 decline to levels below 350 cells/µL (survival probability).
There was a statistically significant association between the presence of CXCR4-using viruses (X4) in the genotype at baseline and an earlier time to CD4 decline below 350 cells/µL (log rank P = 0.0450). The mean time to CD4 decline below 350 was 51.31±3.66 and 34.14±10.61 months for R5- and X4-infected individuals, respectively.