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A MusD Retrotransposon Insertion in the Mouse Slc6a5 Gene Causes Alterations in Neuromuscular Junction Maturation and Behavioral Phenotypes

Figure 6

Anxiety-related behaviors.

A, B : Openfield test, C, D : elevated plus-maze test. Wild-type and heterozygotes values are shown for two age groups, 6 weeks and 7 months old. A. Average time spent per zone of the openfield, in sec., zone 1 being the most peripheral, zone 5 the central zone. B. Average track length per zone (in inches) during the 10 min observation. C. Average time spent in the open or closed arm of the elevated plus-maze. D. Average velocity in the open and closed arms. 6 mice per age group and genotype were observed. * : p<0.05, ** : p<0.01, Mann-Whitney test.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0030217.g006