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Effects of 3,4-Methylenedioxymethamphetamine Administration on Retinal Physiology in the Rat

Figure 5

Effect of MDMA and HT on the scotopic OPs at 7 days.

Four oscillatory potentials (OPs), OP1, OP2, OP3, and OP4, were extracted from scotopic ERGs. (A) Only the effect on the OP3 amplitude and time to peak is shown. (A1) No differences were found both in Control and MDMA groups at 7 days when compared to Baseline ERG. (A2) Time to peak values showed the same behavior for all OPs, in which both Control and MDMA groups presented increased time to peak values at 7 days when compared to Baseline ERG. (B) No differences were found both in Control and MDMA groups in the Sum of OP amplitudes at 7 days when compared to Baseline ERG. *** p<0.001 MDMA group compared to Baseline ERG; ### p<0.001 Control group compared to Baseline ERG. The data are presented as mean ± SEM.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0029583.g005