14-3-3ζ Interacts with Stat3 and Regulates Its Constitutive Activation in Multiple Myeloma Cells
Figure 6
Proposed model of 14-3-3 and Stat3 interaction.
The model illustrated that multiple signaling events, including PKC, Raf1, MEK1/2, ERK1/2 and PP2A, impinge on Stat3 and that 14-3-3ζ serves as an essential coordinator for different pathways to regulate Stat3 activity in myeloma cells.