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Identification of Fluorescent Compounds with Non-Specific Binding Property via High Throughput Live Cell Microscopy

Figure 4

Correlation between NSI values and the chemical structure of the screened ligands.

(A) Combinatorial library has 12 diversities corresponding to the R1 block with each diversity painted a distinct color. Therefore, compounds originating from the same diversity should be structurally similar and close to each other in this space, (b) Compounds from (a) with superior NSI properties are shown in large green circles and those that have passed secondary root hair screening process are shown with red outlines.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0028802.g004