A Meta-Analysis of Array-CGH Studies Implicates Antiviral Immunity Pathways in the Development of Hepatocellular Carcinoma
Figure 2
Profile of chromosomal alterations in all HCC samples (n = 159).
(a), heatmap of CNAs across all chromosomes. (b), the frequencies of CNAs across all chromosomes. Copy number gain and loss events of chromosomal segments were determined using log2-transformed ratio thresholds of 0.141 and −0.136 derived from the k-means clustering analysis. The color brightness is directly proportional to the frequency of CNA. Color red represents copy number gain and color blue represents copy number loss. CNA: copy number alteration.