Insulin Receptor-Mediated Signaling via Phospholipase C-γ Regulates Growth and Differentiation in Drosophila
Figure 7
Expression of wild type (X10) and mutant sl constructs in a mutant sl2 background.
(A) Schematic representation of mutations in the SH2 domains of PLC-γ. (B) Histogram showing the effect of expression of sl constructs on sl2 wing size. n = 100. *p<0.001; error bars represent SEM. (C) Histogram showing the effect of expression of sl constructs on ectopic wing veins of sl2 mutant flies. n = 100. *p<0.001; error bars represent SEM. (D) Histogram showing the effect of expression of sl constructs on extra R7 cells in sl2 mutant eyes. n = 5 eyes each with ≤150 ommatidia per eye. *p<0.001; error bars represent SEM.