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Subchronic Peripheral Neuregulin-1 Increases Ventral Hippocampal Neurogenesis and Induces Antidepressant-Like Effects

Figure 8

Acute locomotor activity does not change in response to NRG1 administration.

NRG1 administration does not affect locomotor activity acutely after administration, either in distance (A, C) or duration (B, D). A, B: First 10 min of activity (distance: p = 0.67; duration: p = 0.96). C, D: 10 min of activity after 10 min habituation (distance: p = 0.60; duration: p = 0.67). Bars represent mean ± SEM. NRG, neuregulin; SAL, saline.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0026610.g008