Hippocampal CA3 Transcriptome Signature Correlates with Initial Precipitating Injury in Refractory Mesial Temporal Lobe Epilepsy
Figure 1
During epilepsy surgery tissue explants from CA3 were obtained for genomic studies. The entire hippocampus was then resected and the specimen was submitted to MRI for texture analysis of the dented gyrus (DG) and, subsequently, to global histological analysis. Arrowed dotted lines indicate PHG-CA1 input-output trajectory. The blue dotted line indicates CA3 and DG limits. Abbreviations: SUB subiculum; GCL, granule cell layer.