Toll-Like Receptors 2 and 4 Regulate the Frequency of IFNγ-Producing CD4+ T-Cells during Pulmonary Infection with Chlamydia pneumoniae
Figure 1
TLR2 and 4 are crucial to control pneumonia-induced loss of body weight of C. pneumoniae-infected mice.
Wild type (n = 24 d0, n = 18 d6, n = 12 d9, n = 6 d12) and TLR2/4 double-deficient mice (n = 24 d0, n = 18 d6, n = 12 d9, n = 6 d12) were infected with C. pneumoniae. At the time point indicated in the graph the body weight of the mice was determined. Bars represent mean and SD of individual mice from two independent experiments. *p<0.001, ANOVA posthoc Holm-Sidak.