New Insight into the Molecular Mechanisms of the Biological Effects of DNA Minor Groove Binders
Figure 5
Differential gene expression profiles induced by H258 and H342.
Venn diagram (left) illustrating overlap between changes identified with H342- and H258-induced differential gene expression profiles. Hierarchical cluster (middle) indicating differential gene expression induced by H258 and H342: red (up-regulated) and green (down-regulated). Gene ontology analysis (right) (P-values represent a Bonferroni-corrected EASE score). These genome-wide gene expression profiles were normalized by untreated H2373 cell gene expression profile.