Fibronectin Matrix Assembly Suppresses Dispersal of Glioblastoma Cells
Figure 2
Aggregate dispersal velocity of 3-glioblastoma cell lines.
This bar graph depicts the spreading velocities of aggregates of U87-MG, LN-229, and U118-MG cells. Data sets included sample sizes of 14, 10, and 11 aggregates, respectively. Aggregate spreading was monitored over an 8-hour period. Movies of the spreading were captured and images at various time points were analyzed. Normalized aggregate diameter was plotted as a function of time, generating a slope, which was used to calculate spreading velocity. As can be seen here, the spreading velocity of aggregates of U87-MG cells is considerably faster than that of either LN-229 or U118-MG (ANOVA, p<0.0001 and Tukey's MCT).