Helios Expression Is a Marker of T Cell Activation and Proliferation
Figure 8
Helios+ expression correlates with Ki-67 expression in vivo.
Murine thymic (left), lymph node (middle) and splenic (right) CD4+ gated cells were divided into Foxp3+ Tregs and Foxp3- cells (top row), and then divided into Helios+ and Helios- subsets (middle), and Ki-67 expression within each subset was analyzed (bottom).