Bioluminescent Imaging Reveals Divergent Viral Pathogenesis in Two Strains of Stat1-Deficient Mice, and in αßγ Interferon Receptor-Deficient Mice
Figure 1
Survival of mice lacking intact IFN signaling.
Kaplan-Meier survival plot of mice infected via the cornea with 2×106 pfu/eye of HSV-1 KOS in control (gray line), 129Stat1−/−(N-term) (solid black line), or AG129 (dashed black line). The plot represents at least 20 mice per model, derived from at least 3 independent experiments.