Simulating EGFR-ERK Signaling Control by Scaffold Proteins KSR and MP1 Reveals Differential Ligand-Sensitivity Co-Regulated by Cbl-CIN85 and Endophilin
Figure 3
A detailed biochemical model of scaffolding action of MP1.
Please refer to “Methods” for the considerations and assumptions used and Supplementary Table S1 for detailed descriptions of their kinetics parameters. “P” denotes protein phosphorylation.