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PRTFDC1 Is a Genetic Modifier of HPRT-Deficiency in the Mouse

Figure 1

Resident-Intruder aggression.

Mice (n = 11–17 per genotype) were tested for intruder aggression in three separate trials, with two days between trials. (A) Percentage of residents that attacked the intruder at each trial. * P<0.05 for overall differences between genotypes within the same trial trial. † P<0.05 comparing Hprt−/0/Tg to wild-type (WT) and Tg within the same trial. (B) Mean latency to attack ± SEM for each genotype during each trial; * P<0.05 comparing Hprt−/0/Tg to all other genotypes within the same trial. (C) Number of attacks ± SEM for each genotype during each trial; * P<0.05 comparing Hprt−/0/Tg to all other genotypes within the same trial.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0022381.g001