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Cytotoxic Effect of Poly-Dispersed Single Walled Carbon Nanotubes on Erythrocytes In Vitro and In Vivo

Figure 6

Effect of AF-SWCNT's on blood count of erythrocytes in mice.

AF-SWCNT's were administered to 6–8 weeks old Swiss mice by the indicated routes (panel A). Mice were administered vehicle (PBS alone) or AF-SWCNT's (100 µg) intravenously, intratracheally, intraperitoneally, or the gavage route, and erythrocyte count was determined at different time intervals. Panel B shows effect of intravenously administered control and acid functionalised SWCNTs on hemoglobin content in blood. Results of a representative experiment have been shown. All data points represent mean ± SEM of three observations. *p<0.01 as compared to PBS administered control groups.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0022032.g006