IL-22 Is Produced by Innate Lymphoid Cells and Limits Inflammation in Allergic Airway Disease
Figure 5
Analysis of cytokines and chemokines in IL-22−/− and congenic controls.
Levels of IL-5. IL-13, IL-10, IFN-γ (IFN) and CCL-17 in BAL fluid, TSLP and IL-33 in lung homogenate and expression of CCL26 in whole lung were analyzed in challenged only (c) and sensitized and challenged (s/c) Il22 deficient (IL-22−/− c, n = 12; IL-22−/− s/c, n = 13) and congenic wild-type controls (IL-22+/+ c, n = 12; IL-22+/+ s/c, n = 13). Each dot represents a single mouse, bar represents mean. Data are from 2 independent experiments. * p<0.05 compared to challenged groups, # p<0.05 compared to all other groups.