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A High Resolution Genome-Wide Scan of HNF4α Recognition Sites Infers a Regulatory Gene Network in Colon Cancer

Figure 8

Motifs overrepresented within the ChIP-enriched regions.

The 10,000 most significant ChIP-enriched regions were analyzed for overrepresented motifs by use of the CEAS tool [43]. Shown are the 10 motifs with the most significant enrichment, while redundant motifs (i.e. multiple motifs for the same transcription factor) were removed. The similarity or dissimilarity of the motifs is visualized by using Weblogo depiction (http://weblogo.berkeley.edu/). Motif enrichment analysis with Genomatix RegionMiner and MATCH [11] are found in Tables S3, S4, S5.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0021667.g008