Cutaneous Squamous Cell Carcinoma (SCC) and the DNA Damage Response: pATM Expression Patterns in Pre-Malignant and Malignant Keratinocyte Skin Lesions
Figure 11
Overall pattern of pATM expression observed in spectrum of AK / CIS / SCC.
This demonstrates greater proportion and increased intensity of nuclear staining of earlier lesions i.e. AK (a) and CIS (b) compared to less extensive and weaker nuclear staining in more advanced SCC (c).