Comparison of Human Memory CD8 T Cell Responses to Adenoviral Early and Late Proteins in Peripheral Blood and Lymphoid Tissue
Figure 3
Expression of homing and activation markers in epitope-specific CD8+ T cells from peripheral blood and tonsils.
Early P-977 pentamer+ and late H-892 pentamer+ CD8+ T cells from peripheral blood (PB) or lymphoid tissue (LT) samples were stained with either T cell activation marker CD25 or lymph node homing receptor CCR7 PE-labeled mAbs. A. Comparison of the proportion of P-977+CD8+ T cells and H-892+CD8+ T cells expressing CCR7 in PB and.LT samples. B. Comparison of the proportion of P-977+CD8+ T cells and H-892+ CD8+ T cells expressing CD25 in PB and LT samples. Recently infected immunocompromised adult (▪). Recently infected immunocompetent adult (•). Remotely infected healthy donor (○).