The Utility of High-Resolution Melting Analysis of SNP Nucleated PCR Amplicons—An MLST Based Staphylococcus aureus Typing Scheme
Figure 3
SNP association map for S. aureus showing the positions of the six selected fragments.
Peaks in the coefficient of association demonstrate regions which, if included in random fragments, are associated with a high –log(1-D) value (i.e., contain informative SNPs). This analysis confirms that the fragments selected using Minimum SNPs and HRMtype include highly informative SNPs.