Interferon-α/β and Anti-Fibroblast Growth Factor Receptor 1 Monoclonal Antibody Suppress Hepatic Cancer Cells In Vitro and In Vivo
Figure 5
Accumulation of anti-FGFR1 mAb in tumor xenografts is enhanced by IFN-α.
A, SCID mice were xenografted with 1×106 HepG2 cells, after which 50 µg of Cy5-conjugated A2C9-1 mAb was intravenously administrated via the tail vein. Mice were then imaged under anesthesia. B, Time course of the Cy5 signal intensity.