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Betaglycan Is Required for the Establishment of Nephron Endowment in the Mouse

Figure 4

Expression of TGFβ isoforms in kidneys of betaglycan mutant mice.

Quantitative real time-PCR assessment of (A) Tgfb1; (B) Tgfb2; and (C) Tgfb3 using RNA derived from age-matched wildtype (solid bars), betaglycan heterozygous (striped bars), and betaglycan null (clear bars) metanephroi. Values are mean + SEM. n = 4–6 RNA pools/genotype/age. Analysis via one-way ANOVA followed by Tukey's post-hoc analysis conducted separately for each gene at each time point. Significant differences (p<0.05) between genotypes are represented by different letters.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0018723.g004