Early Growth Response Gene-2 (Egr-2) Regulates the Development of B and T Cells
Figure 2
A). Absolute number of thymocyte subpopulations in thymus. The ISP cells were defined as CD4−CD8+CD3− (see Fig. 1E). B). The subpopulations of DN cells in thymus were examined by analysis of CD25 and CD44 expression on gated CD4−CD8− DN cells. C). Absolute number of DN subsets in thymus. D). Percentage of CD3+DP cells that develop into CD3+CD4+ or CD3+CD8+ cells in thymus. E). Subpopulations of T cells in lymph nodes and spleen. F). Expression of CD3, TCRβ and CD5 on CD4+ or CD8+ cells in spleens. * p<0.001. The data are representative of more than three experiments in which 3 to 5 mice from each group were used.