HMMerThread: Detecting Remote, Functional Conserved Domains in Entire Genomes by Combining Relaxed Sequence-Database Searches with Fold Recognition
Figure 6
Multiple sequence alignment of the Als2cL family with the RhoGEF domain family.
Residues that are conserved between the two families are highlighted in yellow, those found in only one of them are highlighted in blue and green, respectively. Essential, functional residues retrieved from the CD database are indicated by hash keys. Accession numbers of sequences can be found in Supplemental Table S7.