Interferon Gamma-Dependent Intestinal Pathology Contributes to the Lethality in Bacterial Superantigen-Induced Toxic Shock Syndrome
Figure 5
Effect of IFN-γ deficiency on SEB-induced cytokine responses in vivo.
Age-matched HLA-DR3.IFN-γ+/+ and HLA-DR3.IFN-γ−/− transgenic mice were challenged with SEB (10 µg). Mice were bled at 3 hrs and serum cytokine levels were determined using a multiplex suspension array system (Bio-Plex, Bio-Rad).