Deficiency of Antinociception and Excessive Grooming Induced by Acute Immobilization Stress in Per1 Mutant Mice
Figure 5
Increased serum corticosterone response to immobilization stress in different genotypes.
Serum samples were collected from stressed and non-stressed control of wild type, Per1 mutant and Per2 mutant mice, and assayed with the corticosterone ELISA kit. Data shown represent the mean ± SEM of 4 animals from several independent experiments for each data point. The asterisks (*, p<0.05; **, p<0.01, one way ANOVA) indicate in each genotype, the significant differences of corticosterone level between the stressed mice and the non-stressed mice.