Capsaicin-Induced Changes in LTP in the Lateral Amygdala Are Mediated by TRPV1
Figure 4
Properties of spontaneous PSCs in the absence and presence of TTX.
(A) Continuous recording shows spontaneous EPSCs in the presence of TTX (mEPSCs) from a LA projection neuron under control conditions and 10 min after bath application of capsaicin (1 µM), Vm = −70 mV. (B) Continuous recording shows spontaneous IPSCs in the presence of TTX (mIPSCs) from another LA projection neuron under control conditions and 10 min after bath application of capsaicin (1 µM), Vm = 0 mV. (C) Summary data shows mean frequency of mEPSCs, mIPSCs and sIPSCs under control conditions and in the presence of capsaicin, SEM is indicated by error bars. (D) Amplitude distributions of mIPSCs recorded in under control conditions (black) and in the presence of 1 µM capsaicin (grey). Superimposed lines show cumulative amplitude histograms (p>0.05, Kolmogoroff-Smirnov test). (E) Continuous recording shows spontaneous IPSCs in the absence of TTX (sIPSCs) under control conditions and 10 min after bath application of capsaicin (1 µM), Vm = −70 mV. (F) Amplitude distributions of sIPSCs recorded in under control conditions (black) and in the presence of 1 µM capsaicin (grey). Superimposed lines show cumulative amplitude histograms.