Crowding Alone Cannot Account for Cosolute Effect on Amyloid Aggregation
Figure 8
Effects of high viscosity on amyloid formation kinetic constants.
Relative lag times tlag (A) and elongation lifetimes τel (B) for 50% (w/w) glycerol, TEG and PEG 400, and 30% (w/w) for sorbitol. N.C. corresponds to the reaction in the absence of cosolute, to which the other reactions are compared. (C) The viscosity of each solution, in cP.