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Immune Response to the West Nile Virus in Aged Non-Human Primates

Figure 4

Aged and adult macaques produce robust anti WNV IgM and IgG response.

Panels 1–8 illustrate WNV specific antibody production from Cohort 1 begins about day 10 peaking by day 21 and maintaining in most animals out well past day 45. HI (hemaglutination) assay on the left vertical axis, and IgG and IgM specific Elisa assays are on the right vertical axis reported P/N values (positive over negative), the assay limit of detection is P/N>2 is positive.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0015514.g004