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Renalase Deficiency in Heart Failure Model of Rats—A Potential Mechanism Underlying Circulating Norepinephrine Accumulation

Figure 5

Renalase expression in the kidney increases and subsequently decreases with progression of heart failure post-LAD ligation.

Western blot showing expression of renalase at different time points (24 h–4 weeks) post-LAD ligation. Alpha-tubulin expression is also shown as a housekeeping control. Corresponding graph shows accumulated results from n = 4 for each time point (1.223±0.086 for 24h, 1.556±0.102 for 1w, 0.987±0.056 for 2w, 1.112±0.057 for 3w, 0.945±0.078 for 4w). * p<0.05 vs. 24h, 2w, 3w and 4w. ** p<0.05 vs. 24h.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0014633.g005