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Serum Apolipoproteins C-I and C-III Are Reduced in Stomach Cancer Patients: Results from MALDI-Based Peptidome and Immuno-Based Clinical Assays

Figure 3

Boxplot presentations of MALDI feature 6629 and apoC-I and apoB-100 ELISA assay.

Boxplot presentations of MALDI feature 6629 (A), quantitative ELISA assay for apoC-I (B) and quantitative immunoturbidity-based assay for apoB-100 (C). For A, units represent MALDI-based intensities following quantile normalization according to controls of each sera source (see methods). For B and C, units represent apoC-I and apoB-100 concentration in sera, respectively. For RNTech (Rn), * p-value = 0.002 for A and <0.0001 for B. For Asterand (As), * p-value <0.05 for A and = 0.001 for B; Wilcoxon rank sum test with continuity correction (alternative hypothesis: true location shift is greater than 0).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0014540.g003