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Gene Regulatory Networks from Multifactorial Perturbations Using Graphical Lasso: Application to the DREAM4 Challenge

Figure 2

Influence of the graphical Lasso penalty on network complexity and Bayesian Information.

A: Number of edges versus penalty for data set 3 in the multifactorial challenge with down arrows indicating the chosen associated with (from left to right) AIC, MAX_AUROC, MAX_AUPR and BIC. The horizontal line connects and of the 50 best BIC networks chosen in the ensemble network. B: BIC versus penalty for the five data sets.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0014147.g002