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Interaction of the TNFR-Receptor Associated Factor TRAF1 with I-Kappa B Kinase-2 and TRAF2 Indicates a Regulatory Function for NF-Kappa B Signaling

Figure 2

TRAF2 competes with IKK2 for TRAF1 binding.

The indicated CFP-, YFP- or flag-tagged expression constructs were transfected into HEK-293 cells followed by FRET-microscopy to determine protein interactions. The signals in the CFP- and YFP-channel are shown, as well as a pseudo-colored calculated FRET images.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0012683.g002