Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice
Figure 5
MyD88-deficient mice fed the HFD increases circulating level of cholesterol.
(A–C) Serum cholesterol concentrations were measured at the age of 18 weeks. (A) Free cholesterol, (B) esterified cholesterol and (C) total cholesterol levels. Each genotype of mice was fed the NCD (n = 8) or HFD (n = 6–7). **p<0.01, ***p<0.001 (DE) mRNA levels of LDLR and HMG-CoA reductase (HMG-CoA R) were measured in liver samples at the age of 18 weeks. (n = 6–8) *p<0.05, ***p<0.001.