A Structure-Based Approach for Mapping Adverse Drug Reactions to the Perturbation of Underlying Biological Pathways
Figure 2
An illustration of the network of pathway-ADR associations inferred by our model.
Side-effects are represented as red squares and pathways as blue circles. The full list of 185 associations is available at Table S3. The 22 associations most strongly supported by the literature are circled. Pathways are colored by their KEGG categories.