Metabolic Stress Responses in Drosophila Are Modulated by Brain Neurosecretory Cells That Produce Multiple Neuropeptides
Figure 1
Schematic depiction of a subset of peptidergic lateral neurosecretory cells in the adult Drosophila brain.
The ipc-1 and ipc-2a cells have large cell bodies and co-express the peptides ITP, DTK and sNPF, as well as the enhancer trap Gal4 lines c929 (transcription factor DIMM) and Kurs-6. These neurosecretory cells have axons extending through the corpora cardiaca nerves (NCC) to varicose terminations in the corpora cardiaca, anterior aorta and anterior intestine. Another set of neurons (LNC) in the same cluster as ipc-2a express either sNPF or DTK, but not ITP, c929 or Kurs-6. Their axon trajectories are not known.