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Schizophrenia Gene Networks and Pathways and Their Applications for Novel Candidate Gene Selection

Figure 2

Schizophrenia-specific network.

SZGenes are labeled in red and non-SZGenes in blue. Node area corresponds to its degree in the human interactome. Node shape indicates its cellular location: ellipse for cytoplasm, diamond for extracellular space, triangle for nucleus, square for plasma membrane, and hexagon for unknown location. (A) The extracted schizophrenia-specific network from the human interactome. It has 233 nodes and 436 edges. (B) Network for the 63 nodes that could form clusters by CFinder. (C) Networks for the 170 nodes that could not form clusters by CFinder.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0011351.g002