Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors
Figure 3
Type 2 diabetes susceptibility gene expression in sorted islet cells.
A: mRNA expression of type 2 diabetes susceptibility genes in alpha cells (white bars) and beta cells (black bars), expressed as mean + SEM of all non-diabetic islet donors (n = 16). Statistical significance of pairwise comparisons between alpha and beta cell expression was by Student's T test assuming equal variance. B: Expression of the same data in alpha cells only with male (white bars) and female (black bars) islet donors considered separately (n = 8 each). C: Expression of the same data in beta cells only with male (white bars) and female (black bars) islet donors considered separately (n = 8 each).