Lamin A Rod Domain Mutants Target Heterochromatin Protein 1α and β for Proteasomal Degradation by Activation of F-Box Protein, FBXW10
Figure 3
Expression of chromatin markers in HeLa cells expressing lamin mutants.
Lysates of sorted, transfected cells and untransfected cells (∼50,000 cells per sample) were analyzed by western blotting with antibodies to the indicated proteins. The results shown are representative of three independent experiments.