Evidence for an Essential Deglycosylation-Independent Activity of PNGase in Drosophila melanogaster
Figure 4
Mutation of Pngl resulted in severe delay in development.
(A) genomic map of Pngl with the 2 predicted mRNA, Pngl-RA(light grey) and Pngl RB (dark grey), deletion points in ex14, 18 and 20, indicated by the arrows; (B) Quantitative analysis of Drosophila growth of heterozygotes and homozygotes of the Pngl microdeletion Pngl[ex20]. The number of days after egg laying (AEL) is plotted on the X axis and the number of animals counted is plotted on the Y axis. White indicates the adult, light grey, pupae and dark grey, wandering larvae.