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In-Depth Transcriptome Analysis Reveals Novel TARs and Prevalent Antisense Transcription in Human Cell Lines

Figure 2

(A) Pie chart describing read mappings to different genomic regions.

Almost half of all reads map to known genes (5 UTRs, CDS and 3 UTRs). A large fraction of reads map to regions outside promoters, known genes or terminator regions (red). A very low fraction of all reads map to antisense to protein coding genes. (B) Relative expression densities in different genomics regions. For the antisense strand, a small increase can be seen in promoter and terminator regions. Error bars are one standard deviation calculated across all three samples. (C) Fraction of reads that map to different regions in the genome. In introns, roughly half of all reads map to the antisense strand. Sense in light gray, antisense in dark gray.

doi: https://doi.org/10.1371/journal.pone.0009762.g002