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Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours

Figure 3

APC promoter 1A hypermethylation in parathyroid tumours with a coupling to MEN1 mutations.

Boxplot displaying APC promoter methylation in comparison to MEN1 genotype for all cases where genotype data was available. The endpoints of the boxes represent the first and third quartiles respectively, and the horizontal line corresponds to the median. High APC promoter methylation density is statistically correlated to MEN1 mutational status.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0009472.g003